KCNMB3 Antibody (S40B-18) [DyLight 550]

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC, IP, MA
• Clone: S40B-18
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

KCNMB3 Antibody (S40B-18) [DyLight 550] Summary

• Immunogen: Fusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a
• Localization: Membrane
• Specificity: Detects approx 32 kDa. No cross-reactivity against BKBeta1, BKBeta2, BKBeta3b or BKBeta4.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNMB3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Microarray
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KCNMB3 Antibody (S40B-18) [DyLight 550]

• BK channel subunit beta-3
• BKbeta3
• Hbeta3
• KCNMB2
• KCNMBL
• potassium large conductance calcium-activated channel, subfamily M beta member3
• slo-beta-3
• subfamily M subunit beta-3
• voltage and Ca2+ activated potassium channel Maxi K beta 3subunit

Background

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNMB3