KAT2A/GCN5 Antibody (4F9)

Western Blot: KAT2A/GCN5 Antibody (4F9) [H00002648-M03] - Analysis of GCN5L2 expression in MCF-7 (Cat # L046V1).

Western Blot: KAT2A/GCN5 Antibody (4F9) [H00002648-M03] - Analysis of GCN5L2 expression in A-549 (Cat # L025V1).

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 4F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

KAT2A/GCN5 Antibody (4F9) Summary

• Immunogen: GCN5L2 (AAH32743, 738 a.a. ~ 837 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK
• Specificity: GCN5L2 - GCN5 general control of amino-acid synthesis 5-like 2 (yeast) (4F9)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: KAT2A
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for KAT2A/GCN5 Antibody (4F9)

• EC 2.3.1.48
• GCN5 general control of amino-acid synthesis 5-like 2 (yeast)
• GCN5L2
• GCN5L2GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
• GCN5MGC102791
• General control of amino acid synthesis protein 5-like 2
• General control of amino acid synthesis, yeast, homolog-like 2
• HGCN5
• Histone acetyltransferase GCN5
• histone acetyltransferase KAT2A
• hsGCN5
• K(lysine) acetyltransferase 2A
• KAT2A
• KAT2A/GCN5
• Lysine acetyltransferase 2A
• PCAF-B
• STAF97

Background

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It alsofunctions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA(MIM 164014) in a HAT-independent manner (Mao et al., 2009 (PubMed 19339690)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KAT2A
• Entrez:
  • 2648(Human)
• Uniprot:
  • AAH32743(Human)