ITPA Antibody (RB22150)

Product Discontinued

ITPA Antibody (RB22150) Summary

• Immunogen: This ITPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human ITPA.
• Localization: Cellular Location Cytoplasm. Tissue Location Ubiquitous. Highly expressed in heart, liver, sex glands, thyroid and adrenal gland
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITPA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:100
  • Western Blot 1:1000
• Theoretical MW: 21.446 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Bovine, Chicken, Mouse, Rat and Xenopus.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for ITPA Antibody (RB22150)

• C20orf37
• dJ794I6.3
• EC 3.6.1
• EC 3.6.1.19
• HLC14-06-P
• inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
• Inosine triphosphatase
• inosine triphosphatase-A
• inosine triphosphate pyrophosphatase
• inosine triphosphate pyrophosphohydrolase
• ITPase
• My049 protein
• nucleoside triphosphate diphosphatase
• Putative oncogene protein hlc14-06-p

Background

ITPA hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. The encoded protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency. Two transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITPA
• Uniprot:
  • Q9BY32(Human)