Integrin alpha 7 Antibody (334908) [Allophycocyanin]

C2C12 mouse myoblast cell line was stained with Rat Anti-Mouse Integrin a7 APC-conjugated Monoclonal Antibody (Catalog # FAB3518A, filled histogram) or isotype control antibody (Catalog # IC013A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Mu
• Applications: Flow
• Clone: 334908
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Allophycocyanin

Integrin alpha 7 Antibody (334908) [Allophycocyanin] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 7
  Phe34-Pro1036
  Accession # NP_032424
• Specificity: Detects mouse Integrin alpha 7 in direct ELISAs. Reactivity with other Integrin alpha 7 isoforms was not tested. In direct ELISAs, no cross-reactivity with recombinant mouse Integrin alpha 2, alpha 3, alpha 4, alpha 5, alpha 9, alpha E, alpha X, recombinant human Integrin alpha L, or alpha 11 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: ITGA7
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 7 Antibody (334908) [Allophycocyanin]

• FLJ25220
• integrin alpha 7 chain
• Integrin alpha 7
• integrin alpha-7
• integrin, alpha 7
• ITGA7

Background

Integrin alpha 7 is a transmembrane glycoprotein that forms heterodimers with Integrin  beta 1 to bind Laminin 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Integrin alpha 7 Antibody (FAB3518A)(13)

Publications using FAB3518A

• Mucha, O;Podkalicka, P;?ukowska, M;Po?piech, E;Dulak, J;?oboda, A; miR-378 influences muscle satellite cells and enhances adipogenic potential of fibro-adipogenic progenitors but does not affect muscle regeneration in the glycerol-induced injury model Scientific reports 2023-08-18 [PMID: 37596327] (Flow Cytometry, Mouse)
• Ryo Fujita, Seiya Mizuno, Taketaro Sadahiro, Takuto Hayashi, Takehito Sugasawa, Fumihiro Sugiyama et al. Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity iScience 5/19/2023 [PMID: 37250337]
• Ryo Fujita, Seiya Mizuno, Taketaro Sadahiro, Takuto Hayashi, Takehito Sugasawa, Fumihiro Sugiyama et al. Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity iScience 2023-05-19 [PMID: 37250337] (Flow Cytometry, Mouse)
• I Bronisz-Bu, M Kozakowska, K Pietraszek, M Madej, A Józkowicz, A ?oboda, J Dulak NRF2 Regulates Viability, Proliferation, Resistance to Oxidative Stress, and Differentiation of Murine Myoblasts and Muscle Satellite Cells Cells, 2022-10-21;11(20):. 2022-10-21 [PMID: 36291188] (Flow Cytometry, Mouse)
• AS De la Garz, SA Moore, J Zamora-Pin, EP Hoffman, K Mistry, A Kumar, JB Strober, P Zhao, JH Suh, JD Saba Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice International Journal of Molecular Sciences, 2022-07-08;23(14):. 2022-07-08 [PMID: 35886926] (Flow Cytometry, Mouse)
• Eunhye Kim, Fang Wu, Danbi Lim, Christopher Zeuthen, Yiming Zhang, James Allen et al. Fibroadipogenic Progenitors Regulate the Basal Proliferation of Satellite Cells and Homeostasis of Pharyngeal Muscles via HGF Secretion Frontiers in Cell and Developmental Biology 5/17/2022 [PMID: 35669512]
• Eunhye Kim, Fang Wu, Danbi Lim, Christopher Zeuthen, Yiming Zhang, James Allen et al. Fibroadipogenic Progenitors Regulate the Basal Proliferation of Satellite Cells and Homeostasis of Pharyngeal Muscles via HGF Secretion Frontiers in Cell and Developmental Biology 2022-05-17 [PMID: 35669512] (Flow Cytometry, Mouse)
• CE Xirouchaki, Y Jia, MJ McGrath, S Greatorex, M Tran, TL Merry, D Hong, MJ Eramo, SC Broome, JST Woodhead, RF D'souza, J Gallagher, E Salimova, C Huang, RB Schittenhe, J Sadoshima, MJ Watt, CA Mitchell, T Tiganis Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance Science Advances, 2021-12-15;7(51):eabl4988. 2021-12-15 [PMID: 34910515] (Flow Cytometry, Mouse)
• S Zhou, W Zhang, G Cai, Y Ding, C Wei, S Li, Y Yang, J Qin, D Liu, H Zhang, X Shao, J Wang, H Wang, W Yang, H Wang, S Chen, P Hu, L Sun Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration Cell Res., 2020-08-24;0(0):. 2020-08-24 [PMID: 32839552] (Flow Cytometry, Mouse)
• D van de Vle, J Demmers, XX Nguyen, Y Campos, E Machado, I Annunziata, H Hu, E Gomero, X Qiu, A Bongiovann, CA Feghali-Bo, A d'Azzo Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis Sci Adv, 2019-07-17;5(7):eaav3270. 2019-07-17 [PMID: 31328155] (Flow Cytometry, Mouse)
• Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, Sun K, Sun H, Wang H, Zhang Z, Zhang B, Sheng C, Wang H, Hu P Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion. Cell Res, 2015-05-15;25(6):655-73. 2015-05-15 [PMID: 25976405] (Flow Cytometry, Mouse)
• Westerman K Myospheres are composed of two cell types: one that is myogenic and a second that is mesenchymal. PLoS ONE, 2015-02-23;10(2):e0116956. 2015-02-23 [PMID: 25706128] (Flow Cytometry, Mouse)
• Loh KC, Leong WI, Carlson ME Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. PLoS ONE, 2012-05-14;7(5):e37218. 2012-05-14 [PMID: 22606352] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: ITGA7
• Uniprot:
  • NP_032424()