Hu, Mu, Rt, BvApplications:
ICC/IF, IHC, IHC-P, ICC/IFHost:
Applications: WB, ELISA, PA, AP
ITGA7 encodes integrin alpha chain 7. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 7 undergoes post-translational cleavage within the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. Alpha 7 beta 1 is the major integrin complex expressed in differentiated muscle cells. Splice variants of alpha 7 that differ in both the extracellular and cytoplasmic domains exist in the mouse; however, to date only a single human transcript type has been isolated: it contains extracellular and cytoplasmic domains corresponding to the mouse X2 and B variants, respectively. A unique extracellular splice variant has been identified in human, although it clearly represents a minor species and its biological significance is unclear.
|Product By Gene ID
- integrin alpha-7
- integrin alpha 7 chain
- integrin, alpha 7
Research Areas for Integrin alpha 7
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Bioinformatics Tool for Integrin alpha 7
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