Integrin alpha 11 Antibody [DyLight 488]

• Reactivity: Mu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 488

Integrin alpha 11 Antibody [DyLight 488] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 11
  Phe19-Pro1141
  Accession # P61622
• Specificity: Detects mouse Integrin alpha 11 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) Integrin alpha 11 is observed, and less than 2% cross-reactivity with recombinant mouse (rm) Integrin alpha 2 and rmIntegrin alpha 10 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: ITGA11
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Integrin alpha 11 Antibody [DyLight 488]

• HsT18964
• Integrin alpha 11
• integrin alpha-11
• integrin, alpha 11
• ITGA11

Background

Integrin alpha-11 is a protein that functions as a heterodimer of an alpha and beta subunit, may be involved in attaching muscle tissue to the extracellular matrix, is most highly expressed in the uterus and heart, and is encoded by a gene comprised of 1188 amino acids with a weight of approximately 133 kDa. Studies are being conducted on several diseases and disorders related to this protein including ADHD, lung cancer, adenocarcinoma, thyroiditis, and prostatitis. Integrin alpha-11 has also been shown to have interactions with ITGB1, COL1A1, COL1A2, ACTB, and ACTG1 in pathways such as the focal adhesion, CDK5, NR-kappaB, integrin-mediated cell adhesion, signal transduction, and ECM-receptor interaction pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGA11