ILT5/CD85a/LILRB3 Antibody (4F9) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: Flow, IHC, IHC-Fr
• Clone: 4F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

ILT5/CD85a/LILRB3 Antibody (4F9) [Alexa Fluor® 350] Summary

• Immunogen: Monocyte derived dendritic cells
• Specificity: NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LILRB3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ILT5/CD85a/LILRB3 Antibody (4F9) [Alexa Fluor® 350]

• CD85 antigen-like family member A
• CD85a antigen
• CD85a
• HL9Immunoglobulin-like transcript 5
• ILT5
• ILT-5
• ILT5CD85a
• Leukocyte immunoglobulin-like receptor 3
• leukocyte immunoglobulin-like receptor subfamily B member 3
• leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
• LILRB3
• LIR3
• LIR3CD85A
• LIR-3MGC138403
• member 3
• Monocyte inhibitory receptor HL9
• PIRB

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LILRB3