IL-19 Antibody (019) [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: ELISA
• Clone: 019
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 646

IL-19 Antibody (019) [Janelia Fluor® 646] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-19 (Accession#: AAF06663.1; Met1-Ala177).
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IL19
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IL-19 Antibody (019) [Janelia Fluor® 646]

• IL-10C
• IL19
• IL-19
• interleukin 19
• MDA1
• melanoma differentiation associated protein-like protein
• NG.1Melanoma differentiation-associated protein-like protein
• ZMDA1interleukin-19

Background

IL19 is encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL19