IgM Heavy Chain Antibody (IM260 + IM373 + ICO-30) - IHC-Prediluted

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-P
Clone
IM260 + IM373 + ICO-30
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
IHC-Prediluted

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Catalog# & Formulation Size Price

IgM Heavy Chain Antibody (IM260 + IM373 + ICO-30) - IHC-Prediluted Summary

Immunogen
Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Localization
Cytoplasm, Cell Surface and Secreted
Marker
B-Cell Marker
Specificity
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Isotype
IgG1/IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IGHM
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Human Chromosome Location: 14q32.33 Mol. Weight of Antigen: 50-75 kDa Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10mM PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for IgM Heavy Chain Antibody (IM260 + IM373 + ICO-30) - IHC-Prediluted

  • Constant region of heavy chain of IgM
  • Ig Mu Chain C Region BOT
  • Ig Mu Chain C Region GAL
  • Ig Mu Chain C Region OU
  • immunoglobulin heavy constant mu
  • Immunoglobulin mu chain

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IGHM