IGFLR1/TMEM149 Antibody (905338) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
905338
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

IGFLR1/TMEM149 Antibody (905338) [Alexa Fluor® 350] Summary

Immunogen
Human embryonic kidney cell line HEK293-derived recombinant human IGFLR1
Met1-Pro163
Accession # Q9H665
Specificity
Detects human IGFLR1in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGFLR1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IGFLR1/TMEM149 Antibody (905338) [Alexa Fluor® 350]

  • FLJ22573
  • IGFLR1
  • TMEM149
  • transmembrane protein 149
  • U2 small nuclear RNA auxiliary factor 1-like 4
  • U2(RNU2) small nuclear RNA auxiliary factor 1-like 4
  • U2AF1L4

Background

Insulin Growth Factor-like Family Receptor 1 (IGFLR1) is a 355 amino acid (aa) type 1a transmembrane protein that was identified in a screen for binding partners of human IGFL-1 (1). Mature human IGFLR1 consists of an extracellular domain (ECD) with two putative cysteine-rich domains (CRDs), a transmembrane region, and a cytoplasmic domain (1). Its structure has similarities to TNF receptor family members (1). Over the first 163 aa, human IGFLR1 shares 61% and 59% aa sequence identity with mouse and rat IGFLR1, respectively. In mice, IGFLR1 is expressed primarily on T cells and, similar to the human proteins, mouse IGFLR1 binds the mouse IGFL protein (1). Human IGFL-1 expression is enhanced by TNF-alpha treatment and was shown to be up-regulated in human psoriatic skin samples, suggesting that IGFLR1 may have a role during skin inflammation (1).
  1. Lobito, A.A. et al. (2011) J. Biol. Chem. 286:18969.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for IGFLR1/TMEM149 Antibody (FAB8296U) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB8296U
Alexa Fluor 405 FAB8296V
Alexa Fluor 488 FAB8296G
Alexa Fluor 594 FAB8296T
Alexa Fluor 647 FAB8296R
Alexa Fluor 700 FAB8296N
Alexa Fluor 750 FAB8296S
Phycoerythrin FAB8296P

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Bioinformatics Tool for IGFLR1/TMEM149 Antibody (FAB8296U)

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Contact Information

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Bioinformatics

Gene Symbol IGFLR1
Uniprot