Human IGF2BP3 ELISA Kit (Colorimetric)

ELISA: Human IGF2BP3 ELISA Kit (Colorimetric) [NBP2-82216] - Samples were spiked with high concentrations of Human IGF2BP3 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human IGF2BP3 ELISA Kit (Colorimetric) [NBP2-82216] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, Plasma, Cell supernatant
• Standard Curve Range: 0.31 - 20ng/mL
• Sensitivity: 0.19 ng/mL

Human IGF2BP3 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human IGF2BP3 in samples. No Significant cross-reactivity or interference between Human IGF2BP3 and analogues was observed.
• Standard Curve Range: 0.31 - 20ng/mL
• Sensitivity: 0.19 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 6%
• Intra-Assay: CV% < 5%
• Spike Recovery: average = 95% for serum; average = 96% for EDTA plasma; average = 100% for cell culture media
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: IGF2BP3

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human IGF2BP3 ELISA Kit (Colorimetric)

• CT98
• hKOC
• IGF II mRNA binding protein 3
• IGF2 mRNA-binding protein 3
• IGF-II mRNA-binding protein 3
• IMP-3KH domain-containing protein overexpressed in cancer
• IMP3VICKZ family member 3
• insulin-like growth factor 2 mRNA binding protein 3
• insulin-like growth factor 2 mRNA-binding protein 3
• KH domain containing protein overexpressed in cancer
• KOC1DKFZp686F1078
• VICKZ3cancer/testis antigen 98

Background

The protein encoded by the IGF2BP3 gene is primarily found in the nucleolus, where it can bind to the 5' UTR of theinsulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during latedevelopment. The encoded protein contains several KH domains, which are important in RNA binding and are known to beinvolved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes onother chromosomes. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for IGF2BP3 ELISA Kit (NBP2-82216)(2)

Publications using NBP2-82216

• Mancarella C, Giusti V, Caldoni G et al. Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells Cancer gene therapy 2023-06-23 [PMID: 37353558] (ELISA)
• Wu X, Wang W, Fan S et al. U-shaped association between serum IGF2BP3 and T2DM: A cross-sectional study in Chinese population Journal of diabetes 2023-03-09 [PMID: 36891946]

Bioinformatics

• Gene Symbol: IGF2BP3