IFN-alpha K Antibody (1009720) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB
• Clone: 1009720
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

IFN-alpha K Antibody (1009720) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human IFN-alpha 6/IFNA6
  Leu28-Lys207
  Accession # Q90W0
• Specificity: Detects human IFN-alpha 6/IFNA6 in direct ELISAs and Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: IFNA6
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-alpha K Antibody (1009720) [Alexa Fluor® 532]

• IFNA6
• IFN-alpha 6
• IFNalpha K
• IFN-alpha K
• IFN-kappa
• interferon kappa
• interferon, kappa
• RP11-27J8.1
• UNQ6124/PRO20084

Background

Interferon kappa, also known as IFN-kappa, is a 207 aminoacids protein that in humans is encoded by the IFNK gene. IFN-kappa is a member of the type I interferon family which also includes IFN-alpha, -beta, -epsilon, and -omega. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. Human IFN-kappa has been detected in keratinocytes, monocytes, and monocyte-derived dendritic cells and is reported to have contact-dependent antiviral activity. Human papillomavirus (HPV) 16 oncogene expression, which is necessary for the development of cervical cancer, has been shown to down-regulate human IFN-kappa expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IFNA6