IFN-alpha K Products

Antibodies
IFN-alpha K Antibody (1009720 ...
IFN-alpha K Antibody (1009720) [Un...
MAB10212
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
IFN-alpha K Antibody (3C9)
IFN-alpha K Antibody (3C9)
H00003443-M01
Species: Hu
Applications: WB, ELISA, IP, S-ELISA
Host: Mouse Monoclonal
IFN-alpha K Antibody
IFN-alpha K Antibody
NBP1-31156
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
IFN-alpha K Overexpression Ly ...
IFN-alpha K Overexpression Lysate
NBL1-11845
Species: Hu
Applications: WB
Proteins
Recombinant Mouse IFN-alpha 6 ...
Recombinant Mouse IFN-alpha 6/IFNA...
10207-IF
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human IFN-alpha K ...
Recombinant Human IFN-alpha K GST ...
H00003443-P01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human IFN-alpha K ...
Recombinant Human IFN-alpha K GST ...
H00003443-Q01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP

Description

Interferons (IFN) are a family of cytokines with potent antiviral, antiproliferative and immunomodulatory properties, classified based on their binding specificity to cell surface receptors (1). There are more than a dozen closely related IFN alpha subtypes found in both the human and mouse genome, each sharing about 80% amino acid (aa) sequence homology (2, 3). Mature mouse IFNA6 consists of 166 aa and shares 60% aa identity with human IFNA6. The type I IFNs binds to the interferon alpha receptor (IFNAR) which consists of two subunits: IFNAR1 (alpha -subunit) and IFNAR2 (beta -subunit) (4, 5). Individual IFN alpha subtypes are known to display unique efficacies to viral protection, with IFNA6 displaying the superior efficacy controlling influenza virus infection and disease (6). Treatment with IFNA6 DNA 2 weeks post‐MCMV infection proved effective at inhibiting the development of chronic autoimmune myocarditis. IFNA6 is also able to reduce chronic cardiac inflammation. These findings suggest that immunomodulation of both antiviral and autoimmune responses by IFN DNA immunization may be an avenue for improved viral immunotherapy (7, 8).

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3443
Alternate Names
  • IFN-alpha 6
  • IFN-kappa
  • interferon kappa
  • interferon, kappa
  • RP11-27J8.1
  • UNQ6124/PRO20084
  • IFNA6
  • IFNalpha K
  • IFN-alpha K

Pathways for IFN-alpha K

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Reverse Transcription
Cytokine Production
Cytokine Secretion
Regulation Of Cytokine Production
Response To Virus
Pathogenesis
Secretion

Research Areas for IFN-alpha K

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Cell Cycle and Replication

PTMs for IFN-alpha K

Learn more about PTMs related to IFN-alpha K.

Phosphorylation

Bioinformatics Tool for IFN-alpha K

Discover related pathways, diseases and genes to IFN-alpha K. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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