IFITM1 Antibody - BSA Free

Western Blot: IFITM1 Antibody [NBP1-77171] - 3T3 cell lysate with IFITM1 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry/Immunofluorescence: IFITM1 Antibody [NBP1-77171] - Jurkat cells with IFITM1 antibody at 20 ug/mL.

Immunocytochemistry/ Immunofluorescence: IFITM1 Antibody - BSA Free [NBP1-77171] - Immunofluorescence of IFITM1 in Jurkat cells with IFITM1 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

IFITM1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit IFITM1 Antibody - BSA Free (NBP1-77171) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. Anti-IFITM1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide near the center of human IFITM1. The immunogen is located within amino acids 40 - 90 of IFITM1. Amino Acid Squence: CAFAYSVKSRDRKMVGD
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IFITM1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Western Blot 1-2 ug/ml
• Theoretical MW: 14 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  IFITM1 Peptide (NBP1-77171PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for IFITM1 Antibody - BSA Free

• CD225 antigen
• CD225
• CD225Leu-13 antigen
• IFI17
• IFI17LEU13,9-27
• IFITM1
• interferon induced transmembrane protein 1 (9-27)
• Interferon-induced protein 17
• interferon-induced transmembrane protein 1
• Interferon-inducible protein 9-27
• Leu-13

Background

IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IFITM1 Antibody (NBP1-77171)(2)

Publications using NBP1-77171

• Hariharan A, Qi W, Rehrauer H et al. Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment Molecular Oncology 2022-12-01 [PMID: 36221913]
• Sun S, Frontini F, Qi W, Hariharan A et Al. Endogenous retrovirus expression activates type-I interferon signaling in an experimental mouse model of mesothelioma development Cancer Lett 2021-03-13 [PMID: 33713739]

Bioinformatics

• Gene Symbol: IFITM1
• Uniprot:
  • NP_003632()