Human IL-24 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-24 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL24

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-24 DuoSet ELISA, 15 Plate

• C49A
• FISP
• IL10B
• IL24
• IL-24
• interleukin 24
• MDA-7
• MDA7MOB5
• melanocyte-associated Mda-7
• melanoma differentiation association protein 7
• Melanoma differentiation-associated gene 7 protein
• MOB-5
• ST16
• ST16interleukin-24
• suppression of tumorigenicity 16 (melanoma differentiation)
• Suppression of tumorigenicity 16 protein

Background

Interleukin 24 (IL-24), also known as MDA-7 (melanoma differentiation associated gene-7), is a member of the IL-10 family of helical cytokines. When secreted, IL-24 is a 35- to 40-kDa phosphorylated glycoprotein that may exist as either a monomer or dimer. Cells known to express IL-24 include B cells, CD4+ T cells, NK cells, lymph node dendritic cells, monocytes, melanocytes, and melanoma cells. IL-24 binds two heterodimeric receptor complexes, IL-20 R alpha/IL-20 R beta and IL-22 R/IL-20 R beta.

Publications for IL-24 (DY1965)(9)

Publications using DY1965

• Y Liu, Y Chen, R Sha, Y Li, T Xu, X Hu, L Xu, Q Xie, B Zhao A new insight into the role of aryl hydrocarbon receptor (AhR) in the migration of glioblastoma by AhR-IL24 axis regulation Environment international, 2021-05-31;154(0):106658. 2021-05-31 [PMID: 34082239] (Human)
• LZ Rao, Y Wang, L Zhang, G Wu, L Zhang, FX Wang, LM Chen, F Sun, S Jia, S Zhang, Q Yu, JH Wei, HR Lei, T Yuan, J Li, X Huang, B Cheng, J Zhao, Y Xu, BW Mo, CY Wang, H Zhang IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages Cell Death Differ, 2020-11-03;0(0):. 2020-11-03 [PMID: 33144678] (Mouse)
• GR Kathamuthu, NP Kumar, K Moideen, D Baskaran, S Hissar, BM Shrinivasa, R Sridhar, S Babu Diminished circulating plasma and elevated lymph node culture supernatant levels of IL-10 family cytokines in tuberculous lymphadenitis Cytokine, 2018-06-02;0(0):. 2018-06-02 [PMID: 29871780] (Human)
• A Steinert, I Linas, B Kaya, M Ibrahim, A Schlitzer, P Hruz, K Radulovic, L Terraccian, AJ Macpherson, JH Niess The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models J. Immunol., 2017-09-01;0(0):. 2017-09-01 [PMID: 28864472] (Human)
• Anuradha R, George P, Hanna L, Kumaran P, Chandrasekaran V, Nutman T, Babu S Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis. PLoS Negl Trop Dis, 2014-04-03;8(4):e2762. 2014-04-03 [PMID: 24699268] (Human)
• Shefler I, Pasmanik-Chor M, Kidron D, Mekori Y, Hershko A T cell-derived microvesicles induce mast cell production of IL-24: relevance to inflammatory skin diseases. J Allergy Clin Immunol, 2013-06-12;133(1):217-24.e1-3. 2013-06-12 [PMID: 23768573] (Human)
• Zhu Y, Lv H, Xie Y Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells. Cancer Gene Ther., 2011-06-10;18(9):627-36. 2011-06-10 [PMID: 21660060] (Human)
• Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur. J. Immunol., 2009-10-01;39(10):2779-88. 2009-10-01 [PMID: 19731362] (Human)
• Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C IL-24 modulates IFN-gamma expression in patients with tuberculosis. Immunol. Lett., 2007-12-26;117(1):57-62. 2007-12-26 [PMID: 18199488] (Human)

FAQs for IL-24 (DY1965). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IL24