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1965-IL) stimulates proliferation in the BaF3 mouse pro-B cell line co-transfected with human IL-20 Ra and IL-20 R beta in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-24 (2 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human IL-24 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1965). The ND50 is typically < 0.6 µg/mL." class="big_lightbox" target="_blank">
1965-IL) was serially diluted and captured by Mouse Anti-Human IL‑24 Monoclonal Antibody (Catalog # MAB19652) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human IL‑24 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1965) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
![Neutralization IL-24 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/IL-24_AF1965_Block_Neutralize_8808.jpg)
![N/A IL-24 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL24_DY1965_ELISA_1739.jpg)
![N/A IL-24 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL24_DY278605_ELISA_2406.jpg)
![ELISA IL-24 Antibody [Unconjugated]](http://images.novusbio.com/images/af1965_human-il-24-affinity-purified-polyclonal-ab-elisa-639201854767537702.jpg)
