Human EPCR DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human EPCR DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
PROCR

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY2245.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human EPCR DuoSet ELISA, 15 Plate

  • APC receptor
  • CCCA
  • CCD41
  • CCD41centrosome-associated protein
  • CD201 antigen
  • CD201
  • centrocyclin
  • Endothelial cell protein C receptor
  • endothelial protein C receptor
  • EPCR
  • EPCRMGC23024
  • PROCR
  • protein C receptor, endothelial

Background

EPCR (the Endothelial Protein C Receptor), also known as CD201, is a transmembrane glyoprotein expressed on vascular endothelial cells. EPCR inhibits thrombosis through its interactions with Protein C, activated Protein C (APC), and Coagulation Factors VII, and VIIa. It enhances the activation of Protein C in response to complexes of Thrombin-Thrombomodulin. A soluble form of EPCR inhibits the anti-coagulant activity of APC. EPCR binds to CD11b/CD18 (Mac-1) on monocytes and mediates monocyte adhesion to the vascular endothelium. In addition, it binds to the antigen receptor on gamma/delta T cells, promotes hematopoietic stem cell retention in the bone marrow, and contributes to malaria pathogenicity through binding surface proteins on Plasmodium.

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Publications for EPCR (DY2245)(5)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Filter By Species
Human
(5)
All Species
Showing Publications 1 - 5 of 5.
Publications using DY2245 Applications Species
N Ziliotto, S Meneghetti, E Menegatti, M Baroni, B Lunghi, F Salvi, M Ferracin, A Branchini, D Gemmati, F Mascoli, P Zamboni, F Bernardi, G Marchetti Expression profiles of the internal jugular and saphenous veins: Focus on hemostasis genes Thromb. Res., 2020;191(0):113-124. 2020 [PMID: 32438216] (Human) Human
H Lécuyer, Z Virion, JP Barnier, S Matczak, S Bourdoulou, E Bianchini, F Saller, D Borgel, X Nassif, M Coureuil An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans PLoS Pathog., 2018;14(4):e1006981. 2018 [PMID: 29630665] (Human) Human
AG Vassiliou, A Kotanidou, Z Mastora, C Tascini, G Cardinali, SE Orfanos The H3 Haplotype of the EPCR Gene Determines High sEPCR Levels in Critically Ill Septic Patients Infect Dis Ther, 2018;7(0):3-14. 2018 [PMID: 29549653] (Human) Human
Johansson PI, Sorensen AM, Perner A, Welling KL, Wanscher M, Larsen CF, Ostrowski SR Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity. Crit. Care Med., 2012;40(6):1844-50. 2012 [PMID: 22610188] (Human) Human
Johansson PI, Sorensen AM, Perner A, Welling KL, Wanscher M, Larsen CF, Ostrowski SR High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality. J. Thromb. Haemost., 2011;10(2):207-16. 2011 [PMID: 22151659] (Human) Human

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Product General Protocols

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FAQs for EPCR (DY2245). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

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Bioinformatics

Gene Symbol PROCR