HOXD10 Antibody [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 646

HOXD10 Antibody [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human HOXD10
  Arg153-Thr262
  Accession # P28358
• Specificity: Detects human HOXD10 in direct ELISAs.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HOXD10 Antibody [Janelia Fluor® 646]

• homeo box 4D
• homeo box D10
• homeobox D10
• Homeobox protein Hox-4D
• Homeobox protein Hox-4E
• homeobox protein Hox-D10
• HOX4
• Hox-4.4
• HOX4D
• HOX4DHOX4
• HOX4E
• HOXD10

Background

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as rocker-bottom foot deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.