HOXB7 Antibody (4C6)

Images

 
Immunohistochemistry-Paraffin: HOXB7 Antibody (4C6) [H00003217-M03] - Analysis of monoclonal antibody to HOXB7 on formalin-fixed paraffin-embedded human esophagus. Antibody concentration 1.5 ug/ml
ELISA: HOXB7 Antibody (4C6) [H00003217-M03] - Detection limit for recombinant GST tagged HOXB7 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, RbSpecies Glossary
Applications WB, ELISA, Func, IHC
Clone
4C6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

HOXB7 Antibody (4C6) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
HOXB7 (NP_004493, 55 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAA
Specificity
HOXB7 - homeobox B7
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HOXB7
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Functional
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control. It has been used for IHC-P. Use in Immunohistochemistry reported in scientific literature (PMID: 22914903).
Publications
Read Publications using
H00003217-M03 in the following applications:

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HOXB7 Antibody (4C6)

  • HHO.C1
  • homeo box 2C
  • homeo box B7
  • homeo box c1 protein
  • homeobox B7
  • Homeobox protein HHO.C1
  • Homeobox protein Hox-2C
  • homeobox protein Hox-B7
  • HOX2
  • Hox-2.3
  • HOX2C
  • HOX2CHox-2.3
  • HOXB7

Background

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HOXB7 Antibody (H00003217-M03)(8)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.


Filter By Application
IF/IHC
(1)
All Applications
Filter By Species
Human
(1)
All Species
Showing Publications 1 - 8 of 8.
Publications using H00003217-M03 Applications Species
Xiang W, Jin L, Tingyuan Y et al. HOXB7 acts as an oncogenic biomarker in head and neck squamous cell carcinoma. Cancer Cell Int. 2021-07-24 [PMID: 34303375]
Zhenfeng S, Hao Z, Situ J et al. Long non-coding RNA SNHG8 promotes prostate cancer progression through repressing miR-384 and up-regulating HOXB7. J Gene Med. 2021-01-15 [PMID: 33450101]
Zhou T, Fu H, Dong B et al. HOXB7 mediates cisplatin resistance in esophageal squamous cell carcinoma through involvement of DNA damage repair. Thorac Cancer. 2019-09-30 [PMID: 31568655]
Zhao H, Li X, Guan W et al. Impact of co-blocking the costimulatory signals on immune-related genes after high-risk rabbit corneal allograft using 2nd-generation DNA sequencing technology. Genet Mol Biol. 2019-07-18 [PMID: 31323080]
Dai L, Hu W, Yang Z et al. Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis. Lab Invest. 2019-05-03 [PMID: 30664713]
Hui Li, Lu-Yan Shen, Wan-Pu Yan et al. Deregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo. PLoS One. 2015-06-15 [PMID: 26076456]
Kraiklang R, Pairojkul C, Khuntikeo N et al. A novel predictive equation for potential diagnosis of cholangiocarcinoma. PLoS One. 2014-02-28 [PMID: 24586698]
Nguyen Kovochich A, Arensman Met al. HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer 2013-02-01 [PMID: 22914903] (IF/IHC, Human) IF/IHC Human

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Bioinformatics

Gene Symbol HOXB7
Entrez
OMIM
Uniprot