HLA DR/DP Antibody (HL-40) - BSA Free

Immunohistochemistry-Paraffin: HLA DR/DP Antibody (HL-40) [NB500-408] - Immunohistochemistry staining of human small intestine (paraffin-embedded sections) with anti-HLA-DR/DP (HL-40).

Staining of human small intestine (paraffin-embedded sections) with anti-HLA-DR+DP (HL-40). Commercially tested by LifeSpan BioSciences.

• Reactivity: Hu, Po
• Applications: IHC, IP, CyTOF-ready
• Clone: HL-40
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

HLA DR/DP Antibody (HL-40) - BSA Free Summary

• Immunogen: Raji Burkitt's lymphoma cell line
• Specificity: The antibody HL-40 reacts with common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: HLA-DRA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:50
• Application Notes: This antibody is Cytof ready.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for HLA DR/DP Antibody (HL-40) - BSA Free

• FLJ51114
• histocompatibility antigen HLA-DR alpha
• HLA class II histocompatibility antigen, DR alpha chain
• HLA-DRA1
• major histocompatibility complex, class II, DR alpha
• MHC cell surface glycoprotein
• MHC class II antigen DRA
• MLRW

Background

The antibody is useful for detection of HLA-DR and HLA-DP positive B-cells, T-cells and monocytes in cell suspensions, in frozen sections as well as in formalin fixed paraffin embedded tissue sections. The antibody is also useful for characterization of leukemias and lymphomas. In experimental settings it can be used for selective removal of antigen carrying cells by complement mediated cytotoxicity. The antibody has excellent staining properties in histology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HLA-DRA
• Entrez:
  • 3122(Human)