HLA DR/DP Products

Antibodies

Description

Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.

Bioinformatics

Entrez Human
Product By Gene ID 3122
Alternate Names
  • MHC cell surface glycoprotein
  • FLJ51114
  • HLA class II histocompatibility antigen, DR alpha chain
  • MHC class II antigen DRA
  • histocompatibility antigen HLA-DR alpha
  • HLA-DRA1
  • MLRW
  • major histocompatibility complex, class II, DR alpha

Research Areas for HLA DR/DP

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Biology
Diabetes Research
Immunology

PTMs for HLA DR/DP

Learn more about PTMs related to HLA DR/DP.

Methylation
Phosphorylation
Acetylation
Demethylation
Reduction
Deacetylation
Citrullination

Bioinformatics Tool for HLA DR/DP

Discover related pathways, diseases and genes to HLA DR/DP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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