Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Rabbit Monoclonal
WB, Flow, IHC, IHC-P, IP, CyTOF-readyHost:
Applications: WB, Flow, IHC, IHC-P, IP, CyTOF-ready
Host: Mouse Monoclonal
Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
|Product By Gene ID
- MHC cell surface glycoprotein
- HLA class II histocompatibility antigen, DR alpha chain
- MHC class II antigen DRA
- histocompatibility antigen HLA-DR alpha
- major histocompatibility complex, class II, DR alpha
Bioinformatics Tool for HLA DR/DP
Discover related pathways, diseases and genes to HLA DR/DP. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.