HLA DR/DP Antibody (HL-38) [FITC]

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Product Details

Summary
Reactivity Hu, PoSpecies Glossary
Applications Flow
Clone
HL-38
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

HLA DR/DP Antibody (HL-38) [FITC] Summary

Immunogen
Raji Burkitt's lymphoma cell line
Epitope
This antibody binds to a common epitope on the b-chain of human HLA-DR and HLA-DP.
Specificity
The antibody HL-38 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
HLA-DRA
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 106 cells in a suspension.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Purity
Protein A purified

Alternate Names for HLA DR/DP Antibody (HL-38) [FITC]

  • FLJ51114
  • histocompatibility antigen HLA-DR alpha
  • HLA class II histocompatibility antigen, DR alpha chain
  • HLA-DRA1
  • major histocompatibility complex, class II, DR alpha
  • MHC cell surface glycoprotein
  • MHC class II antigen DRA
  • MLRW

Background

Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB500-406APC
DyLight 350 Labeled NB500-406UV
DyLight 405 Labeled NB500-406V
DyLight 488 Labeled NB500-406G
DyLight 680 Labeled NB500-406FR
DyLight 755 Labeled NB500-406IR
PE Labeled NB500-406PE
PerCP Labeled NB500-406PCP

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HLA DR/DP NB500-407

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Bioinformatics

Gene Symbol HLA-DRA