HLA DR/DP Antibody (Bra-14) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
Bra-14
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

HLA DR/DP Antibody (Bra-14) [DyLight 594] Summary

Immunogen
Human REH cells
Localization
Cell surface
Specificity
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Isotype
IgG3 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HLA-DRA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HLA DR/DP Antibody (Bra-14) [DyLight 594]

  • FLJ51114
  • histocompatibility antigen HLA-DR alpha
  • HLA class II histocompatibility antigen, DR alpha chain
  • HLA-DRA1
  • major histocompatibility complex, class II, DR alpha
  • MHC cell surface glycoprotein
  • MHC class II antigen DRA
  • MLRW

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-48006AF350
Alexa Fluor 405 NBP2-48006AF405
Alexa Fluor 488 NBP2-48006AF488
Alexa Fluor 532 NBP2-48006AF532
Alexa Fluor 594 NBP2-48006AF594
Alexa Fluor 647 NBP2-48006AF647
Alexa Fluor 700 NBP2-48006AF700
Alexa Fluor 750 NBP2-48006AF750
Allophycocyanin NBP2-48006APC
Allophycocyanin/Cy7 NBP2-48006APCCY7
Biotin NBP2-48006B
DyLight 350 NBP2-48006UV
DyLight 405 NBP2-48006V
DyLight 488 NBP2-48006G
DyLight 550 NBP2-48006R
DyLight 594 NBP2-48006DL594
DyLight 650 NBP2-48006C
DyLight 680 NBP2-48006FR
DyLight 755 NBP2-48006IR
FITC NBP2-48006F
HRP NBP2-48006H
Janelia Fluor 549 NBP2-48006JF549
Janelia Fluor 646 NBP2-48006JF646
PE NBP2-48006PE
PE/Atto594 NBP2-48006PEATT594
PE/Cy5.5 NBP2-48006PECY55
PE/Cy7 NBP2-48006PECY7
PerCP NBP2-48006PCP

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Bioinformatics Tool for HLA DR/DP Antibody (NBP2-48006DL594)

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Bioinformatics

Gene Symbol HLA-DRA