Histone Deacetylase 8/HDAC8 Antibody [PerCP]

• Reactivity: Hu, Mu
• Applications: WB, ChIP
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: PerCP

Histone Deacetylase 8/HDAC8 Antibody [PerCP] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human HDAC8 isoform 1
  Met1-Val377 (Leu31Pro)
  Accession # Q9BY41
• Specificity: Detects human HDAC8 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: HDAC8
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP)
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Histone Deacetylase 8/HDAC8 Antibody [PerCP]

• EC 3.5.1.98
• HD8
• HDAC8
• HDACL1
• Histone Deacetylase 8
• histone deacetylase-like 1
• RPD3

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HDAC8