Histamine N-Methyltransferase/HNMT Antibody (2G24) - Azide and BSA Free

Western Blot: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug] - Detection against Immunogen (37.73 KDa) .

ELISA: Histamine N-Methyltransferase/HNMT Antibody (2G24) [H00003176-M12-50ug] - Detection limit for recombinant GST tagged HNMT is 0.1 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 2G24
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Histamine N-Methyltransferase/HNMT Antibody (2G24) - Azide and BSA Free Summary

• Immunogen: HNMT (NP_008826, 184 a.a. ~ 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
• Isotype: IgG3 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: HNMT
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Histamine N-Methyltransferase/HNMT Antibody (2G24) - Azide and BSA Free

• EC 2.1.1.8
• Histamine NMethyltransferase
• Histamine N-Methyltransferase
• HMT
• HNMT
• HNMT-S1
• HNMT-S2

Background

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HNMT
• Entrez:
  • 3176(Human)
• OMIM:
  • 600807(Human)
• Uniprot:
  • NP_008826(Human)