HISPPD1 Antibody

Images

 
Western Blot: HISPPD1 Antibody [NBP2-16836] - Sample (30 ug of whole cell lysate) A: Raji B: K562 5% SDS PAGE gel, diluted at 1:3000.
Immunohistochemistry-Paraffin: HISPPD1 Antibody [NBP2-16836] - Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

HISPPD1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human HISPPD1. The exact sequence is proprietary.
Localization
Cytoplasm; cytosol
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPIP5K2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
138 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Xenopus laevis (94%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HISPPD1 Antibody

  • diphosphoinositol pentakisphosphate kinase 2FLJ21506
  • EC 2.7.4.21
  • EC 2.7.4.24
  • HISPPD1histidine acid phosphatase domain containing 1
  • Histidine acid phosphatase domain-containing protein 1
  • hsVIP2
  • inositol heptaphosphate kinase 2
  • inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
  • InsP6 and PP-IP5 kinase 2
  • KIAA0433FLJ23463
  • VIP1 homolog 2
  • VIP2IP7K2

Background

Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PPIP5K2
Uniprot