HERC1 Antibody

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Immunoprecipitation: HERC1 Antibody [NBP1-05968] - Whole cell lysate from HeLa cells. Antibodies: Affinity purified rabbit anti-HERC1 antibody used for IP at 3 mcg/mg lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

       

Order Details

HERC1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 125 and 175 of human hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1 using the numbering given in entry NP_003913.3 (GeneID 892
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HERC1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 - 5 ug/mg lysate
Application Notes
This antibody is not recommended for Western Blot analysis.
Publications
Read Publication using NBP1-05968.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HERC1 Antibody

  • EC 6.3.2
  • guanine nucleotide exchange factor p532
  • hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1(CHC1)-like domain (RLD) 1
  • hect domain and RCC1-like domain 1
  • HECT domain and RCC1-like domain-containing protein 1
  • p532probable E3 ubiquitin-protein ligase HERC1
  • p619EC 6.3.2.-

Background

HERC1 (HECT domain and RCC1-like domain-containing protein 1) belongs to the HERC family of ubiquitin ligases. It is involved in membrane traffic via its ability to bind clathrin and its guanine nucleotide exchange factor (GEF) activity for Arf and Rab. HERC1 has been found to interact with TSC2 (tuberous sclerosis complex 2) and may be involved with its destabilization. Alternative names for HERC1 include p532 and p619.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HERC1 Antibody (NBP1-05968)(1)

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Secondary Antibodies

 

Isotype Controls

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HERC1 NBP1-05968

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Bioinformatics

Gene Symbol HERC1
Entrez
Uniprot