GTF3C2 Antibody

Western Blot: GTF3C2 Antibody [H00002976-B01P] - Analysis of GTF3C2 expression in Hela S3 NE.

Immunocytochemistry/Immunofluorescence: GTF3C2 Antibody [H00002976-B01P] - Analysis of purified antibody to GTF3C2 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: GTF3C2 Antibody [H00002976-B01P] - GTF3C2 MaxPab polyclonal antibody. Western Blot analysis of GTF3C2 expression in Hela NE.

Western Blot: GTF3C2 Antibody [H00002976-B01P] - Analysis of GTF3C2 expression in transfected 293T cell line by GTF3C2 polyclonal antibody. Lane1:GTF3C2 transfected lysate(100.21 KDa). Lane2:Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

GTF3C2 Antibody Summary

• Immunogen: GTF3C2 (NP_001030598.1, 1 a.a. - 911 a.a.) full-length human protein. MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGAWELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPNPPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSHRLLPTP
• Specificity: Reacts with general transcription factor IIIC, polypeptide 2, beta 110kDa.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: GTF3C2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence
  • Western Blot
• Application Notes: This antibody is reactive against cell and transfected lysate in WB, IF and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GTF3C2 Antibody

• general transcription factor 3C polypeptide 2
• general transcription factor IIIC, polypeptide 2, beta 110kDa
• KIAA0011general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD)
• TF3C-beta
• TFIIIC 110 kDa subunit
• TFIIIC110Transcription factor IIIC 110 kDa subunit
• TFIIIC-BETA
• Transcription factor IIIC subunit beta

Background

General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GTF3C2
• Entrez:
  • 2976(Human)
• Uniprot:
  • NP_001030598.1(Human)