GPR3 Antibody - BSA Free

Immunohistochemistry-Paraffin: GPR3 Antibody - BSA Free [NBP1-02376] - Staining of human brain after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

• Reactivity: Hu, Pm, Pm, Eq
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

GPR3 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPR3.
• Epitope: N-Terminus extracellular domain
• Specificity: Human GPR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CASKIN2 (53%), INPPL1 (47%).
• Predicted Species: Equine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 10 ug/ml
• Application Notes: .

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Bovine (88%), Rabbit (88%), Elephant (82%), Panda (82%), Porcine (82%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR3 Antibody - BSA Free

• ACCA
• G protein-coupled receptor 3
• GPR3

Background

GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPR3
• Entrez:
  • 2827(Human)
• Uniprot:
  • P46089(Human)