Glycine Receptor Alpha 1 Antibody

Western Blot: Glycine Receptor Alpha 1 Antibody [H00002741-D01P] - Analysis of GLRA1 expression in transfected 293T cell line by GLRA1 polyclonal antibody.Lane 1: GLRA1 transfected lysate(51.70 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Glycine Receptor Alpha 1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: GLRA1 (NP_000162.2, 1 a.a. - 449 a.a.) full-length human protein. MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
• Specificity: GLRA1 - glycine receptor, alpha 1 (startle disease/hyperekplexia),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GLRA1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Glycine Receptor Alpha 1 Antibody

• GLRA 1
• GLRA1
• Glycine receptor 48 kDa subunit
• Glycine receptor strychnine-binding subunit
• glycine receptor subunit alpha-1
• glycine receptor, alpha 1 (startle disease/hyperekplexia)
• glycine receptor, alpha 1
• HKPX1
• MGC138878
• MGC138879
• STHE

Background

The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GLRA1
• Entrez:
  • 2741(Human)
• Uniprot:
  • NP_000162.2(Human)