Glycine N-Methyltransferase/GNMT Antibody (OTI8A3) [Allophycocyanin/Cy7]

• Reactivity: Hu, Mu
• Applications: WB, Flow
• Clone: OTI8A3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

Glycine N-Methyltransferase/GNMT Antibody (OTI8A3) [Allophycocyanin/Cy7] Summary

• Immunogen: Full length recombinant protein of human Glycine N-Methyltransferase/GNMT (NP_061833) produced in HEK293T cells.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Gene: GNMT
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Glycine N-Methyltransferase/GNMT Antibody (OTI8A3) [Allophycocyanin/Cy7]

• EC 2.1.1.20
• Glycine NMethyltransferase
• Glycine N-Methyltransferase
• GNMT

Background

GNMT is encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNMT