Immunocytochemistry/ Immunofluorescence: GLP/EHMT1 Antibody [NBP1-77400] - Antibody was tested at 1:200 in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).
Immunohistochemistry: GLP/EHMT1 Antibody [NBP1-77400] - IHC analysis of EMHT1 in mouse prostate using DAB with hematoxylin counterstain.
This EHMT1 antibody is useful for ICC/IF and Immunohistochemistry-paraffin sections. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. Use in Western blot reported in reported in scientific literature (PMID: 30858340). Knockdown validation (PMID: 30858340).
Read Publications using NBP1-77400 in the following applications:
The transcription repressor EHMT1 is a histone methyltransferase that might be important in the G0/G1 cell cycle transition. In children affected with Kleefstra Syndrome, EHMT1 is mutated and seems to mis-regulate normal cellular transitions, and cause hypotonia and intellectual disability. It has been implicated in epigenetic modifications related to learning and memory formation or impairment. Finally, the translocation of this gene and erroneous protein expression have been correlated to mental retardation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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