Recombinant Human GIPC1 His Protein

SDS-Page: Recombinant Human GIPC1 Protein [NBP1-45278] - 15% SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human GIPC1 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-333 of Human GIPC1
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL AEALDERLGD FAFPDEFVFD VWGAIGDAKV GRY

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: GIPC1
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 38.2 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 20% glycerol, 1 mM DTT, 0.1 M NaCl, and 1 mM EDTA
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human GIPC1 His Protein

• C19orf3chromosome 19 open reading frame 3
• GAIP C-terminus-interacting protein
• GIPC PDZ domain containing family, member 1
• GIPCRGS-GAIP-interacting protein
• GLUT1 C-terminal binding protein
• GLUT1CBP
• IGF-1 receptor interacting protein 1
• MGC15889
• MGC3774
• NIP
• PDZ domain-containing protein GIPC1
• regulator of G-protein signalling 19 interacting protein 1
• RGS19IP1IIP-1
• SEMCAP
• SYNECTIIN
• SYNECTIN
• Tax interaction protein 2
• TIP-2RGS19-interacting protein 1

Background

GIPC1 is a PDZ domain containing protein that interacts with RGS-GAIP and the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating Clathrin-coated vesicular trafficking. GIPC also associates with membrane bound Semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain. Recombinant human GIPC1 protein, fused to at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: GIPC1