GHRH Antibody

Product Discontinued

GHRH Antibody Summary

• Immunogen: This GHRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-34 amino acids from the N-terminal region of human GHRH.
• Localization: Cellular Location Secreted.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GHRH
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10 - 1:50
  • Western Blot 1:1000
• Theoretical MW: 12.447 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.9 mg/ml
• Purity: Ammonium sulfate precipitation

Alternate Names for GHRH Antibody

• GHRFsomatocrinin
• GRF
• growth hormone releasing hormone
• Growth hormone-releasing factor
• Growth hormone-releasing hormone
• INN
• MGC119781
• sermorelin
• Somatocrinin
• somatoliberin
• somatorelin

Background

GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this protein are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GHRH
• Uniprot:
  • P01286(Human)