GCAP3 Antibody - Azide and BSA Free

Western Blot: GCAP3 Antibody [H00009626-D01P] - Analysis of GUCA1C expression in transfected 293T cell line by GUCA1C polyclonal antibody.Lane 1: GUCA1C transfected lysate(23.80 KDa).Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: GCAP3 Antibody [H00009626-D01P] - Analysis of antibody to GUCA1C on HeLa cell. Antibody concentration 20 ug/ml.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

GCAP3 Antibody - Azide and BSA Free Summary

• Immunogen: GUCA1C (NP_005450.2, 1 a.a. - 209 a.a.) full-length human protein. MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFIDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GUCA1C
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is useful for Western Blot

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GCAP3 Antibody - Azide and BSA Free

• GCAP3GCAP 3
• guanylate cyclase activator 1CMGC120159
• guanylyl cyclase-activating protein 3
• MGC120158

Background

GCAP3, also known as GUCA1C or Guanylyl cyclase-activating protein 3, has a 209 amino acid isoform that is 24 kDa and a short 196 amino acid isoform that is approx. 22 kDa; commonly found in retina; in conditions of low free calcium ions concentration stimulates guanylyl cyclase 1 (GC1) and GC2 and when the concentration is elevated inhibits guanylyl cyclases, which is very important for the recuperation of the dark state of rod photoreceptors following light exposure. Disease research has linked this protein with cone dystrophy, neuronitis, and retinitis. This protein has shown interactions with GUCA1A, GUCA1B, GUCY2D, GUCY2F, and CNGA3 proteins in the pathways such as the visual cycle in retinal rods, olfactory transduction, and phototransduction pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GUCA1C
• Uniprot:
  • NP_005450.2(Human)