Gastrin-releasing Peptide R/GRPR Antibody

Product Discontinued

Gastrin-releasing Peptide R/GRPR Antibody Summary

• Immunogen: Synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GRPR
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1 ug/ml
  • Western Blot 1 ug/ml
• Application Notes: WB: Detects an approx. 65 kDa protein representing the various glycosylated forms of GRP-R.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for Gastrin-releasing Peptide R/GRPR Antibody

• Gastrin-releasing Peptide R
• gastrin-releasing peptide receptor
• Gastrinreleasing PeptideR
• Gastrin-releasing PeptideR
• GRP-preferring bombesin receptor
• GRPR
• GRP-R

Background

GRPR mediates signals of cellular proliferation and it has been shown to be aberrantly expressed in several cancers such as colon, lung, ovary, pancreas and prostate. It also expressed at very high levels in normal pancreas and at lower levels in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach and uterus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Gastrin-releasing Peptide R/GRPR Antibody (NB100-74434)(1)

Publication using NB100-74434

• Kashani R. Engineered Antibody and Neuropeptide Mediated Radionuclide Targeting in Prostate Cancer. Queen Mary University of London. 2010-01-01

Bioinformatics

• Gene Symbol: GRPR
• Entrez:
  • 2925(Human)
• Uniprot:
  • P30550(Human)