Galectin-10 Antibody (561603) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: Flow
• Clone: 561603
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594
• Concentration: Please see the vial label for concentration. If unlisted please contact technical services.

Galectin-10 Antibody (561603) [Alexa Fluor® 594] Summary

• Immunogen: E. coli-derived recombinant human Galectin-10
  Met1-Arg142
  Accession # Q05315
• Specificity: Detects human Galectin-10 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Galectin-1, -2,
  -3, -4, -7, -8, or -9/Ecalectin is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLC

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 0.25-1 ug/10^6 cells
• Application Notes: Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
• Preservative: 0.09% Sodium Azide
• Concentration: Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Galectin-10 Antibody (561603) [Alexa Fluor® 594]

• Charcot-Leyden crystal proteinLGALS10A
• CLC
• EC 3.1.1.5
• eosinophil lysophospholipase
• GAL10
• Gal-10
• galectin 10
• Galectin10
• Galectin-10
• LGALS10
• LPPL_HUMAN
• Lysolecithin acylhydrolase
• MGC149659

Background

Galectin-10 (also eosinophil lysophospholipase and Charcot-Leyden Crystal protein) is a 16 kDa member of the lectin family of proteins. It is expressed intracellularly by eosinophils, basophils and CD25⁺ Treg cells. Although originally believed to possess lysophospholipase activity, this has been shown to be incorrect. It is known to bind lysophospholipase and its inhibitors, and to bind mannose in a very unusual manner. Human Galectin-10 is 142 amino acids (aa) in length. There is one galectin domain (aa 6-138) that contains two dimerization motifs (aa 6-10 and 131-135). Two molecular weight isoforms of 15 and 14 kDa have been described. Human Galectin-10 has no known structural counterpart in rodents.    

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLC
• Uniprot:
  • Q05315()