Galactosylceramidase/GALC Antibody [Janelia Fluor® 646]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 646

Galactosylceramidase/GALC Antibody [Janelia Fluor® 646] Summary

• Immunogen: galactosylceramidase. (Uniprot# P54803)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GALC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Galactosylceramidase/GALC Antibody [Janelia Fluor® 646]

• EC 3.2.1.46
• Galactocerebrosidase
• Galactocerebroside beta-galactosidase
• galactosylceramidase (Krabbe disease)
• Galactosylceramidase
• Galactosylceramide beta-galactosidase
• Galactosylceraminidase
• GALC
• GALCERase

Background

The GALC gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALC