G-CSFR/CD114 Antibody (LMM741) - BSA Free

Flow Cytometry: G-CSFR/CD114 Antibody (LMM741) [NBP3-09162] - Separation of human neutrophil granulocytes (red-filled) from CD114 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD114 (LMM741) purified antibody (concentration in sample 9 ug/ml) GAM APC.

Flow Cytometry: G-CSFR/CD114 Antibody (LMM741) [NBP3-09162] - Surface staining pattern of human peripheral blood stained using anti-human CD114 (LMM741) purified antibody (concentration in sample 9 ug/ml) GAM APC.

• Reactivity: Hu
• Applications: Flow
• Clone: LMM741
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

G-CSFR/CD114 Antibody (LMM741) - BSA Free Summary

• Additional Information: Clone LMM741 was used by HLDA to establish CD designation.
• Immunogen: CHO cells transfected with human G-CSFR/CD114
• Specificity: The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CSF3R
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1 ug/ml

Reactivity Notes

This antibody does not react with: Mouse

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for G-CSFR/CD114 Antibody (LMM741) - BSA Free

• CD114 antigen
• CD114
• colony stimulating factor 3 receptor (granulocyte)
• CSF3R
• Csfgr
• G-CSF R
• G-CSF receptor
• GCSFR
• G-CSFR
• GCSFRG-CSF-R
• granulocyte colony-stimulating factor receptor

Background

GCSF Receptor is encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSF3R