FXYD3 Antibody - BSA Free

Western Blot: FXYD3 Antibody - BSA Free [NBP3-46285] - COLO 320 cells were subjected to SDS PAGE followed by western blot with (FXYD3 antibody) at dilution of 1:400

Immunohistochemistry: FXYD3 Antibody - BSA Free [NBP3-46285] - Immunohistochemistry of paraffin-embedded human breast cancer using (FXYD3 antibody) at dilution of 1:100

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

FXYD3 Antibody - BSA Free Summary

• Immunogen: FXYD domain containing ion transport regulator 3. (Uniprot# Q14802)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FXYD3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for FXYD3 Antibody - BSA Free

• Chloride conductance inducer protein Mat-8
• FXYD domain containing ion transport regulator 3
• FXYD domain-containing ion transport regulator 3
• Mammary tumor 8 kDa protein
• MAT8MAT-8
• phospholemman-like protein
• Phospholemman-like
• PLMLMGC111076

Background

FXYD3, also known as FXYD domain-containing ion transport regulator 3, consists of 3 isoforms, a 87 amino acid isoform that is 9 kDa, a 113 amino acid isoform that is 12 kDa, and a 144 amino acid that is 15 kDa; is membrane located, functions as an inducer of a hyperpolarization-activated chloride current when expressed in Xenopus oocytes, and may be a modulator capable of activating endogenous oocyte channels. Current research is being performed on several diseases and disorders including adenocarcinoma, pancreatic, ductal adenocarcinoma, intrahepatic cholangiocarcinoma, colorectal cancer, cholangiocarcinoma prostate carcinoma, melanoma, pancreatic cancer, pancreatitis, prostate cancer, breast cancer, and prostatitis. The FXYD3 protein has also shown an interaction with SERBP1, FBXL12, NR4A1, MAPK6 and NUDT3, in the regulation of catalytic activity, ion transport, and chloride transport pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FXYD3