FUSIP1 Antibody (1A6) - Azide and BSA Free

Western Blot: FUSIP1 Antibody (1A6) [H00010772-M03] - Analysis of FUSIP1 expression in Hela S3 NE (Cat # L013V3).

Immunocytochemistry/Immunofluorescence: FUSIP1 Antibody (1A6) [H00010772-M03] - Analysis of monoclonal antibody to FUSIP1 on HeLa cell. Antibody concentration 10 ug/ml

Immunohistochemistry-Paraffin: FUSIP1 Antibody (1A6) [H00010772-M03] - Analysis of monoclonal antibody to FUSIP1 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml

Western Blot: FUSIP1 Antibody (1A6) [H00010772-M03] - Analysis of FUSIP1 expression in transfected 293T cell line by FUSIP1 monoclonal antibody (M03), clone 1A6. Lane 1: FUSIP1 transfected lysatE (22.2 KDa). Lane 2: Non-transfected lysate.

ELISA: FUSIP1 Antibody (1A6) [H00010772-M03] - Detection limit for recombinant GST tagged FUSIP1 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 1A6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

FUSIP1 Antibody (1A6) - Azide and BSA Free Summary

• Immunogen: FUSIP1 (AAH05039, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE
• Specificity: FUSIP1 - FUS interacting protein (serine/arginine-rich) 1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SRSF10
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FUSIP1 Antibody (1A6) - Azide and BSA Free

• 40 kDa SR-repressor protein
• FLJ43846
• FUS interacting protein (serine-arginine rich) 1
• FUS-interacting protein (serine-arginine rich) 2
• FUS-interacting serine-arginine-rich protein 1
• FUSIP1DKFZp686H0644
• FUSIP2
• neural-salient SR protein
• NSSR
• serine/arginine-rich splicing factor 10
• serine-arginine repressor protein (40 kDa)
• SFRS13
• SFRS13A
• Splicing factor SRp38
• splicing factor, arginine/serine-rich 13
• Splicing factor, arginine/serine-rich 13ATLS-associated protein with Ser-Arg repeats
• SR splicing factor 10
• SRp38
• SRrp40TLS-associated protein with SR repeats
• TASR1TLS-associated SR protein
• TASR2FUS interacting protein (serine/arginine-rich) 1
• TASRFLJ30749
• TLS-associated protein TASR
• TLS-associated serine-arginine protein 1
• TLS-associated serine-arginine protein 2
• TLS-associated serine-arginine protein

Background

This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SRSF10
• Entrez:
  • 10772(Human)
• OMIM:
  • 605221(Human)
• Uniprot:
  • AAH05039(Human)