Recombinant Mouse FTO His Protein

• Reactivity: Mu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Mouse FTO His Protein Summary

• Description: Mouse FTO (aa 2-502) fused at the N-terminus to a His-tag.
  
  Source: E. coli

  Uniprot ID: Q8BGW1

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: FTO
• Purity: >90% SDS-PAGE
• Endotoxin Note: <1EU/ug purified protein (LAL test; Lonza).

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Liquid. 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90% SDS-PAGE

Alternate Names for Recombinant Mouse FTO His Protein

• Alpha-ketoglutarate-dependent dioxygenase FTO
• EC 1.14.11.-
• fat mass and obesity associated
• Fat mass and obesity-associated protein
• FTO
• KIAA1752protein fto
• MGC5149

Background

Fat mass and obesity-associated protein (FTO) is a novel protein and a member of the non-heme dioxygenase (Fe(II)- and 2-oxoglutarate-dependent dioxygenases) superfamily. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.

FTO antibodies are useful tools for lipid metabolism research and obesity studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

FAQs for FTO Recombinant Protein (NBP3-18144). (Showing 1 - 1 of 1 FAQ).

1. Do you have any antibodies against FTO, where you can indicate the sequence of the immunogen?
   • With regards to other FTO antibodies that we do list the peptide sequence for, the immunogen sequence for catalog number NB110-60935 can be found in the range of amino acids 400-505. Many of the exact immunogen sequences used for our products are proprietary and cannot be disclosed. In these instances we try to provide a reasonable amino acid range to help in your decision.

Bioinformatics

• Gene Symbol: FTO
• Uniprot:
  • Q8BGW1(Mouse)