Frizzled-7 Antibody

Product Discontinued

Frizzled-7 Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human FZD7 / Frizzled 7.
• Epitope: N-terminal extracellular domain of human
• Specificity: Human FZD7 / Frizzled 7. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FZD1 (60%), FZD2 (60%).
• Predicted Species: Opossum (100%), Xenopus (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FZD7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4 ug/ml

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Turkey (85%), Chicken (85%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Frizzled-7 Antibody

• frizzled (Drosophila) homolog 7
• frizzled homolog 7 (Drosophila)
• Frizzled, drosophila, homolog of, 7
• Frizzled7
• Frizzled-7
• fz-7
• FZD7
• FzE3frizzled-7
• hFz7

Background

FZD7, a Frizzled Receptor, is a receptor for Wnt signaling proteins. FZD7 downregulates the functions of the tumor suppressor gene APC and thereby enhances beta catenin-mediated signals. FZD7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FZD7
• Entrez:
  • 8324(Human)