Hu, Bt, Bv, Canine, Hamster, Primate, Mouse, Opossum, Rabbit, Rat, MonkeyApplications:
Applications: WB, ELISA, PA
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]
Bioinformatics Tool for Frizzled-7
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