Flow, CyTOF-ready, ICC/IFHost:
Hu, Mu, Rt, Bt, Bv, Ca, Ha, Pm, Ma-Op, Pm, RbApplications:
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]
Bioinformatics Tool for Frizzled-7
Discover related pathways, diseases and genes to Frizzled-7. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.