Frizzled-7 Antibody (patent anti-FZD7) [DyLight 550]

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clone: patent anti-FZD7
• Clonality: Monoclonal
• Host: Human
• Conjugate: DyLight 550

Frizzled-7 Antibody (patent anti-FZD7) [DyLight 550] Summary

• Description: The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
  
  Patent #: US20220356256
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: FZD7
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: FZD7
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Frizzled-7 Antibody (patent anti-FZD7) [DyLight 550]

• frizzled (Drosophila) homolog 7
• frizzled homolog 7 (Drosophila)
• Frizzled, drosophila, homolog of, 7
• Frizzled7
• Frizzled-7
• fz-7
• FZD7
• FzE3frizzled-7
• hFz7

Background

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FZD7