Frizzled-6 Antibody (211435)

• Reactivity: Mu
• Applications: WB
• Clone: 211435
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: LYOPH

Frizzled-6 Antibody (211435) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-6
  His19-Val153 (predicted)
  Accession # Q61089
• Specificity: Detects mouse Frizzled-6 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Frizzled-5 or recombinant mouse Frizzled-1, -2, -3, -4, -5, -7, -8, or -9 is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: FZD6
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Frizzled-6 Antibody (211435)

• frizzled (Drosophila) homolog 6
• frizzled homolog 6 (Drosophila)
• Frizzled6
• Frizzled-6
• FZ6
• fz-6
• FZD6
• Hfz6
• seven transmembrane helix receptor

Background

Frizzled-6 is a member of the Frizzled/Smoothened family of G-protein coupled receptors that mediate the Wnt beta-Catenin signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Frizzled-6 Antibody (MAB1526)(1)

Publication using MAB1526

• Baksh D, Boland GM, Tuan RS Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation. J. Cell. Biochem., 2007-08-01;101(5):1109-24. 2007-08-01 [PMID: 17546602] (Flow Cytometry, Human)

Bioinformatics

• Gene Symbol: FZD6
• Uniprot:
  • Q61089()