Frizzled-4 Antibody

Images

 
Immunohistochemistry-Paraffin: Frizzled-4 Antibody [NLS4911] - Anti-FZD4 / Frizzled 4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: Frizzled-4 Antibody [NLS4911] - Skeletal Muscle
Immunohistochemistry-Paraffin: Frizzled-4 Antibody [NLS4911] - Analysis of anti-FZD4 / Frizzled 4 antibody with human kidney.
Immunohistochemistry-Paraffin: Frizzled-4 Antibody [NLS4911] - Anti-FZD4 / Frizzled 4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bt, Bv, Ca, Ch, Eq, Ha, Pm, Pm, Rb, Ma-Op, Tr, XpSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Frizzled-4 Antibody Summary

Immunogen
Synthetic 13 amino acid peptide from C-terminus of human FZD4 / Frizzled 4.
Localization
Cell Membrane
Specificity
Human FZD4 / Frizzled 4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Xenopus (92%), Turkey (100%), Opossum (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FZD4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 25 ug/ml

Reactivity Notes

Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Platypus (100%), Lizard (92%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Frizzled-4 Antibody

  • CD344 antigen
  • CD344
  • EVR1
  • exudative vitreoretinopathy 1
  • FEVR
  • frizzled (Drosophila) homolog 4
  • frizzled homolog 4 (Drosophila)
  • Frizzled4
  • Frizzled-4
  • Fz-4
  • FZD4
  • FZD4S
  • FzE4
  • GPCR
  • hFz4
  • MGC34390
  • WNT receptor frizzled-4

Background

FZD4 is a Frizzled Receptor involved in mediating Wnt signaling. A splicing variant of frizzled-4, FZD4s, encodes a soluble-type positive regulator of the Wnt signaling pathway. Mutations in FZD4 are associated with retinal angiogenesis. FZD4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain. FZD4 expression has not been reported in several cancer cell lines studied. ESTs have been isolated from adipose, adrenal, B-cell/lung/testis, bone marrow, brain, breast, colon, embryo, gallbladder, head/neck, heart, heart/melanocyte/uterus, kidney, liver, liver/spleen, lung, placenta, prostate, skeletal muscle, skin, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FZD4
Entrez