Frizzled-3 Antibody

Western Blot: Frizzled-3 Antibody [NBP1-30940] - Western blot analysis of Frizzled-3 Antibody on NIH-3T3, diluted at 1:1000 with 7.5% SDS PAGE gel.

Western Blot: Frizzled-3 Antibody [NBP1-30940] - Western blot analysis of Frizzled-3 Antibody on HeLa S3 (lane A), MOLT4 (lane B), and Raji (lane C), diluted at 1:1000 with 7.5% SDS PAGE gel.

Product Discontinued

Frizzled-3 Antibody Summary

• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Frizzled-3. The exact sequence is proprietary.
• Localization: Membrane, Multi-pass membrane protein
• Specificity: Antibody reactive against peptide, detects immunogen. Further validation in progress.
• Predicted Species: Rat (100%), Chicken (100%), Xenopus (100%), Rhesus Macaque (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FZD3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Antibody reactive against peptide, detects immunogen. Further validation in progress.
• Theoretical MW: 76 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for Frizzled-3 Antibody

• frizzled (Drosophila) homolog 3
• frizzled homolog 3 (Drosophila)
• Frizzled3
• Frizzled-3
• Fz-3
• FZD3
• hFz3

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: FZD3
• Entrez:
  • 7976(Human)
• Uniprot:
  • Q9NPG1(Human)