Frizzled-3 Antibody

Product Discontinued

Frizzled-3 Antibody Summary

• Immunogen: Peptide with sequence C-DDQRSKAGSIHSK corresponding to internal region according to NP_059108.1.
• Epitope: C-DDQRSKAGSIHSK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FZD3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
• Application Notes: WB: Preliminary experiments in human brain (frontal cortex), mouse brain and rat brain lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Frizzled-3 Antibody

• frizzled (Drosophila) homolog 3
• frizzled homolog 3 (Drosophila)
• Frizzled3
• Frizzled-3
• Fz-3
• FZD3
• hFz3

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Frizzled-3 Antibody (NB100-93450)(1)

Publication using NB100-93450

• You J, Nguyen AV, Albers CG et al. Wnt Pathway-Related Gene Expression in Inflammatory Bowel Disease. Dig Dis Sci 2007-10-16 [PMID: 17939044]

Bioinformatics

• Gene Symbol: FZD3
• Entrez:
  • 7976(Human)
  • 14365(Mouse)
  • 266715(Rat)
• Uniprot:
  • NP_059108.1(Human)