Frataxin Antibody (rFXN/2124) [Janelia Fluor® 585]

Product Discontinued

Frataxin Antibody (rFXN/2124) [Janelia Fluor® 585] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary) (Uniprot: Q16595)
• Localization: Cytoplasmic (Mitochondria)
• Marker: Mitochondrial Marker
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FXN
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Frataxin Antibody (rFXN/2124) [Janelia Fluor® 585]

• CyaY
• EC 1.16.3.1
• FA
• FARRmitochondrial
• frataxin
• Friedreich ataxia protein
• Friedreich ataxia
• Fxn
• X25MGC57199

Background

Frataxin encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FXN